Found 295 matching trials
Delayed Tolerance Through Mixed Chimerism PHASE1 This study will examine the safety and effectiveness of a bone marrow trans...
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Active Not Recruiting
Location
Massachusetts General Hospital
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Continuous Alloreactive T Cell Depletion and Regulatory T Cell Expansion for the Treatment of Steroid-refractory or Dependent Chronic GVHD PHASE2 Phase II multicenter, Canadian only study - open to 25 subjects. Study open...
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Hospital Maissoneuve
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The Efficacy and Safety Assessment of Allogeneic γδ T Cells in Patients With MRD-positive AML After Allo-HSCT EARLY_PHASE1 The purpose of this study is to evaluate the efficacy and safety of allogen...
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Institute of Hematology & Blood Diseases Hospital
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Genetically Engineered PBMC and PBSC Expressing NY-ESO-1 TCR After a Myeloablative Conditioning Regimen to Treat Patients With Advanced Cancer PHASE1 This phase I clinical trial evaluates the safety and feasibility of adminis...
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UCLA / Jonsson Comprehensive Cancer Center
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A Pilot Study of Immunotherapy Including Haploidentical NK Cell Infusion Following CD133+ Positively-Selected Autologous Hematopoietic Stem Cells in Children With High Risk Solid Tumors or Lymphomas PHASE1 This is a pilot clinical trial investigating the addition of haploidentical...
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St. Jude Children's Research Hospital
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Efficacy and Safety of Targeted Intramyocardial Delivery of Auto CD34+ Stem Cells for Improving Exercise Capacity in Subjects With Refractory Angina PHASE3 The purpose of the study is to assess the safety and efficacy of targeted i...
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Multiple Locations
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Haploidentical Hematopoietic Stem Cell Transplantation With Ex Vivo TCR Alpha/Beta and CD19 Depletion in Pediatric Hematologic Malignancies PHASE1 This single arm pilot phase I study with safety run-in is designed to estim...
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Washington University School of Medicine
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TCRαβ-depleted Progenitor Cell Graft With Early Memory T-cell DLI, Plus Selected Use of Blinatumomab, in naïve T-cell Depleted Haploidentical Donor Hematopoietic Cell Transplantation for Hematologic Malignancies PHASE1 This is a phase I, prospective clinical trial studying the safety and feasi...
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St. Jude Children's Research Hospital
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CD7 CAR-T Combined With Autologous Hematopoietic Stem Cell Transplantation PHASE1 This is a single-arm, open-label, phase I/II clinical trial initiated by in...
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The First Affiliated Hospital of Zhengzhou University, Department of Oncology
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Nonmyeloablative Haploidentical Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Sickle Cell Disease PHASE1 Background:
Peripheral blood stem cell transplantation procedures are used...
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Active Not Recruiting
Location
National Institutes of Health Clinical Center
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